Platelet Rich Plasma (PRP) Injections in Medical Research


There have been numerous research and peer reviewed papers published about platelet rich plasma therapy. Here is a selection of some recently published papers for musculoskeletal medicine and aesthetic medicine.

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Musculoskeletal medicine


Gobbi A, Lad D, Karnatzikos G. The effects of repeated intra-articular PRP injections on clinical outcomes of early osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc. 2014 Apr 20. [View abstract]

Abrams GD, Frank RM, Fortier LA, Cole BJ. Platelet-rich Plasma for Articular Cartilage Repair. Sports Med Arthrosc. 2013 Dec;21(4):213-9. doi: 10.1097/JSA.0b013e3182999740. [View abstract]

Filardo G, Kon E, Roffi A, Di Matteo B, Merli ML, Marcacci M. Platelet-rich plasma: why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration. Knee Surg Sports Traumatol Arthrosc. 2013 Nov 26. [Download full article in PDF format]

Halpern B, Chaudhury S, Rodeo SA, Hayter C, Bogner E, Potter HG, Nguyen J. Clinical and MRI outcomes after platelet-rich plasma treatment for knee osteoarthritis. Clin J Sport Med. 2013 May;23(3):238-9.
[View abstract]

Vetrano M, Castorina A, Vulpiani MC, Baldini R, Pavan A, Ferretti A. Platelet-Rich Plasma Versus Focused Shock Waves in the Treatment of Jumper's Knee in Athletes. Am J Sports Med. 2013 Feb 13.
[View abstract]

Martinelli N, Marinozzi A, Carnì S, Trovato U, Bianchi A, Denaro V. Platelet-rich plasma injections for chronic plantar fasciitis. Int Orthop. 2012 Dec 19.
[View abstract]

Wasterlain AS, Braun HJ, Harris AH, Kim HJ, Dragoo JL. The Systemic Effects of Platelet-Rich Plasma Injection. Am J Sports Med. 2012 Dec 4.
[View abstract]

Gobbi A, Karnatzikos G, Mahajan V and Malchira S. Platelet-Rich Plasma Treatment in Symptomatic Patients With Knee Osteoarthritis Preliminary Results in a Group of Active Patients. Sports Health: A Multidisciplinary Approach 2012 4: 162
[View abstract]

Monto RR. Platelet-Rich Rich Plasma is More Effective than Cortisone for Chronic Severe Plantar Fasciitis. Paper presented at: The American Academy of Orthopaedic Surgeons; 2012 February 7-11; San Francisco, USA.
[View abstract]

Sánchez M, Guadilla J, Fiz N, Andia I. Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip. Rheumatology (Oxford). 2012 Jan;51(1):144-50. Epub 2011 Nov 10.
[View abstract]

Filardo G, Kon E, Pereira Ruiz MT, Vaccaro F, Guitaldi R, Di Martino A, Cenacchi A, Fornasari PM, Marcacci M. Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: single- versus double-spinning approach. Knee Surg Sports Traumatol Arthrosc. 2011 Dec 28. [Epub ahead of print]
[View abstract]

Kon E, Mandelbaum B, Buda R, Filardo G, Delcogliano M, Timoncini A, Fornasari PM, Giannini S, Marcacci M. Arthroscopy. Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis. 2011 Nov;27(11):1490-501. Epub 2011 Aug 10.
[View abstract]

Filardo G, Kon E, Buda R, Timoncini A, Di Martino A, Cenacchi A, Fornasari PM, Giannini S, Marcacci M. Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis. Knee Surg Sports Traumatol Arthrosc. 2011 Apr;19(4):528-35. Epub 2010 Aug 26.
[View abstract]

Gosens T, Peerbooms JC, van Laar W, den Oudsten BL. Ongoing Positive Effect of Platelet-Rich Plasma Versus Corticosteroid Injection in Lateral Epicondylitis: A Double-Blind Randomized Controlled Trial With 2-year Follow-up. Am J Sports Med. 2011 Jun;39(6):1200-8.
[View abstract]

Wang-Saegusa A, Cugat R, Ares O, Seijas R, Cuscó X, Garcia-Balletbó M. Infiltration of plasma rich in growth factors for osteoarthritis of the knee short-term effects on function and quality of life. Arch Orthop Trauma Surg. 2011 Mar;131(3):311-7. Epub 2010 Aug 17.
[View abstract]

Kon E, Buda R, Filardo G, Di Martino A, Timoncini A, Cenacchi A, Fornasari PM, Giannini S, Marcacci M. Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee Surg Sports Traumatol Arthrosc. 2010 Apr;18(4):472-9. Epub 2009 Oct 17.
[View abstract]

Peerbooms JC, Sluimer J, Bruijn DJ, Gosens T. Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am J Sports Med. 2010 Feb;38(2):255-62.
[Download full article in PDF format]

Sampson S, Gerhardt M, Mandelbaum B. Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Curr Rev Musculoskelet Med. 2008 Dec;1(3-4):165-74.
[Download full article in PDF format]

Sánchez M, Anitua E, Orive G, Mujika I, Andia I. Platelet-rich therapies in the treatment of orthopaedic sport injuries. Sports Med. 2009;39(5):345-54.
[View abstract]

de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA. 2010 Jan 13;303(2):144-9.
[View abstract]

Creaney L, Hamilton B. Growth factor delivery methods in the management of sports injuries: the state of play. Br J Sports Med. 2008 May;42(5):314-20.
[View abstract]

Hall MP, Band PA, Meislin RJ, Jazrawi LM, Cardone DA. Platelet-rich plasma: current concepts and application in sports medicine. J Am Acad Orthop Surg. 2009 Oct;17(10):602-8.
[View abstract]

Peerbooms, J. C., Sluimer, J., Bruijn, D. J., Gosens, T. Positive Effect of an Autologous Platelet Concentrate in Lateral Epicondylitis in a Double-Blind Randomized Controlled Trial: Platelet-Rich Plasma Versus Corticosteroid Injection With a 1-Year Follow-up. Am J Sports Med 38: 255-262
[View abstract]

Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006 Nov;34(11):1774-8.
[View abstract]

Eppley BL, Woodell JE, Higgins J. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast Reconstr Surg. 2004 Nov;114(6):1502-8.
[View abstract]

Aesthetic medicine


Eppley BL. Platelet-rich plasma: A review of biology and applications in plastic surgery. Plast Reconstr Surg 118: 147e, 2006
[View abstract]

Bhanot S et al. Current applications of platelet gels in facial plastic surgery. Facial Plast Surg 18, 27-33, 2002
[View abstract]

Pietrzak WS et al. Platelet Rich Plasma: Biology and new technology. J Craniofacial Surgery, 16: 1043-1054, 2005
[View abstract]